Musculoskeletal Pain: Types, Causes, Symptoms & Treatment

Musculoskeletal Pain: Types, Causes, Symptoms & Treatment

"Best medical decision I ever made! The stem cell procedure is quick, easy and has no recovery down time! Great alternative to surgery if that is an option."

By R3 Stem Cell Pakistan

Musculoskeletal pain is an umbrella term that refers to pain that affects bones, muscles, nerves, ligaments, and tendons. Trauma from injuries or disease can onset a range of mild to severe musculoskeletal discomfort.

This pain can interfere with your daily life by either striking one area or spreading throughout the body. In this blog post, we will discuss different types, causes, and symptoms of Musculoskeletal Pain. The article also focuses on different kinds of traditional and latest treatments for musculoskeletal pain.

Table of Contents

Types of Musculoskeletal Pain:

People experience musculoskeletal pain differently. Some patients report encountering sudden intense pain known as Acute Musculoskeletal Pain. While other patients sustain Chronic Musculoskeletal pain which lasts around 3-6 months. However, the pain is categorized based on the elements it targets.

Back Pain:

The most prevalent musculoskeletal discomfort is back pain. Muscle strain, inflammation, disease, disc fracture, spinal lesions, degenerative conditions, and osteoarthritis are all possible causes of back pain.

Myalgia or Muscle Pain:

Myalgia is a type of pain that affects soft tissues that connect bones, muscles, and organs. This can occur due to infections, spasms, cramps, tumors, or injuries. Inappropriate blood flow to muscles, disease and some medications can also onset muscle pain. In aggravated cases, myalgia affects tendons, ligaments, organs, and bones as well. Muscle pains are usually momentary and severe. Painful muscle twitching or contractions may also occur due to cramps.

Joint Pain:

Pain, stiffness, inflammation tenderness, and limited flexibility in joints are all characteristics of arthritis. Patients with arthritis frequently experience chronic joint pain, which can be extremely difficult to manage.

Bone Pain:

Pain and soreness in the bone, usually after a fracture or injury, cause musculoskeletal bone pain. Other reasons behind bone pain include osteoporosis, infections, systemic illness, and bone tumor. Bone is usually more uncomfortable than muscle or tendon pain. This is because it can be deep, sharp with a stabbing sensation, or dull but persistent.

Tendon and Ligament Pain:

Ligaments and tendons are strong tissues that connect our bones and joints. Overusing or tearing these connective tissues and onset of tendon and ligament pain. These include inflammation, strains, sprains, tendinitis, and tenosynovitis pains.

Nerve Compression Pain:

Conditions that cause significant nerve stress, including sciatic pain, carpal tunnel syndrome, tarsal tunnel syndrome, and cubital tunnel syndrome, contribute to nerve compression pain. Nerve compression can also arise from repetitive use like leaning on elbows or sitting for long hours in one position. Conditions like gout or arthritis also cause nerve compression pain.

Chest Pain:

Inflammation in the cartilage of the rib cage or costochondritis causes musculoskeletal chest pain.

Causes of Musculoskeletal Pain:

There are plenty of habits, injuries, disorders, and conditions that lead to musculoskeletal pain. These causes can include, sports injuries, car accidents fall injuries these pains also include non-musculoskeletal pain.


Injuries that affect bones muscles, ligaments, and tendons include car accidents, falls, or sports injuries. Trauma from injuries like strains, sprains, bone fractures, and dislocation of joints is one of the leading causes of musculoskeletal pain.

Musculoskeletal Disorders:

These conditions have an impact on the bones, joints, ligaments, and muscles. Some of the common musculoskeletal disorders are autoimmune conditions, arthritis, lupus ankylosing spondylitis, and osteoporosis.


Structural disfigurements in joints, bones, and muscles due to issues like muscular dystrophy or cerebral palsy also contribute to musculoskeletal pain.

Occupational or Habitual Contributors:

Overusing joints, muscles, and ligaments at work or while playing can contribute to musculoskeletal pain. Bad posture, long hours of sitting, or physical inactivity can also lead to musculoskeletal discomforts. Other reasons may include tumors, cancer, or infections in bones, soft tissues, or muscles.

Speech and Language Therapy:

Speech and language therapy can assist the patient with the ability to communicate properly through either speech or sign language. The speech-language pathologists can also teach how to use communication technologies like a computer and a voice synthesizer. This therapy can also at times aid with eating and swallowing issues.

Symptoms of Musculoskeletal Pain:

Depending on the reasons and location musculoskeletal pain varies in different patients. Typical of this condition symptoms encompass:


–       Inflammation

–       Stiffness

–       Swelling

–       Limited range of movement

–       Fatigue

–       Muscle spasms

–       Cracking sound from the joints

–       Weakness

–       Twitching

–       Disturned Sleep

Treatments for Musculoskeletal Pain

Most of the traditional treatments necessitate combining different therapies and treatments to improve the patient’s condition. Some of the popular treatments for musculoskeletal pain can include the following.


Medications are important in managing your musculoskeletal disease. They operate in conjunction with other treatments such as exercise, sleep, assistive technology, and a nutritious diet. Your doctor will prescribe drugs based on your condition and symptoms to help combat inflammation and soreness. These drugs can be administered orally or through injections directly in the painful area. However, these drugs have a severe risk of dependency and side effects.


Physical therapy entails muscle training and exercises that help with the restoration of movement, flexibility, strength, balance, and mobility. PT sessions can improve musculoskeletal pain significantly. Though in severe cases patients might need assistance from other therapies. 

These can include therapeutic massages or chiropractic manipulation. In certain cases, a physiotherapist can supervise the use of assistive devices if the patient requires any. These devices can include braces, taping, and lumbar support. Other complementary therapies like vitamin, herbal, or mineral supplements and acupuncture can also help some patients.


Surgical procedures are always reserved as the last resort. This is because these surgeries can be highly dangerous and can entail a lot of complications for the patients including the risk of rejection. These procedures can include joint replacement, arthroscopy, soft tissue, and cartilage repair, and joint replacement.

Innovative Treatments for Musculoskeletal Pain: Stem Cell Therapy

Cellular therapy is a well-known regenerative treatment that uses stem cells to improve the body’s natural regenerative abilities. The body’s natural defense against disease, damage, and premature aging comprises these cells. Doctors have been investigating these cells for the past 3 decades to combat various ailments. Stem cells entail anti-inflammatory, immunomodulatory, proliferative, and differentiation capacities. Due to these characteristics stem cells can treat a wide range of chronic, autoimmune, genetic, and traumatic illnesses, including musculoskeletal pain.

Effects of Stem Cell Therapy on Patients of Musculoskeletal Pain:

Stem cells extracted from the umbilical cord or the amniotic fluid exhibit high amounts of Immuno-modulatory pluripotent properties. Evidence from clinical data shows that these capacities are very beneficial for musculoskeletal patients. When administered to patients with musculoskeletal pain, these cells merge with the microenvironment to avoid unfavorable immune reactions. This enables them to respond quickly to the damage and inflammation without intervention from the immune system. 

After merging, stem cells self-replicate, resulting in pools of unclaimed raw cells. These cells then identify damage and differentiate per the requirements. Stem cells are the only cells in our bodies that can differentiate into functioning lineage-specific cells. In patients with musculoskeletal pain, these cells can repair the affected cells, muscles, nerves, and tissues. Furthermore, stem cells help to re-establish neural cells. Physicians observed the following improvement in the patients with musculoskeletal disorder treatment with stem cell therapy.

–       Stem cells not only target the symptoms but also the underlying causes of musculoskeletal pain. 

–       Stem cells have an impact on our body’s original cells. This improves overall signal communication and causes afflicted locations to respond quickly.

–       These stem cells differentiate into various specialized cells to help minimize the damage. Stem cells turn into ligaments, tendons, muscles, bones, and organ cells. These specialized cells then replace the damaged cells in the body.

–       Repair or replacement of damaged tissues improves flexibility, range of motion, muscle strength, and tone.

–       Furthermore, stem cells help with nerve growth and differentiate into nerve fibers or neural cells. This improves blood flow to different parts of the body along with motor and sensory functioning.

–       By creating adequate hydration or collagen, stem cells fight bone inflammation and edema. This, in combination with cartilage regeneration, can improve a variety of deformities, and joint, and chest pains.

R3 Stem Cell Pakistan:

The FDA in the United States regulated procedures involving the umbilical cord or amniotic fluid. This is because, in addition to providing excellent results for musculoskeletal sufferers, these cells are free of ethical and medical problems. 

In Pakistan, organizations like the R3 Stem Cell Pakistan team of experts help people suffering from various medical conditions. If you or anyone you know suffers from musculoskeletal pain feel free to reach out.

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